Stem Cell Therapy (2021) and Leber's hereditary optic neuropathy (LHON)

2021

Leber's hereditary optic neuropathy (LHON) an inherited optic nerve disorder, causes degeneration of the retinal ganglion cells (RGC). Stem cells differentiate into various cells with regenerative properties. This 2021 review of studies points out that Mesenchymal stem cells (MSC) particularly, can differentiate into a broad spectrum of cells that are able to repair or replace neural, photoreceptor, corneal, epithelial, and fibroblast cells, and are therefore poised to benefit optic neuropathy conditions.

Mohana Devi S, Abishek Kumar B, Mahalaxmi I, Balachandar V. (2021). Leber's hereditary optic neuropathy: Current approaches and future perspectives on Mesenchymal stem cell-mediated rescue. Mitochondrion. Sep;60:201-218.